A Buyer’s Guide to 4-Trifluoromethoxyphenylboronic Acid (CAS 139301-27-2)

4-Trifluoromethoxyphenylboronic acid, CAS 139301-27-2, is an arylboronic acid used as a coupling reagent in organic synthesis, including Suzuki–Miyaura cross-coupling workflows. Buyers should verify the compound’s identity, assay, impurity profile, packaging, and shipment requirements against the needs of their project before ordering. Its molecular formula is C₇H₆BF₃O₃, and its molecular weight is approximately 205.93 g/mol. Maison Chemical can discuss product specifications and sourcing requirements with B2B customers upon inquiry.

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Key Takeaways

• Confirm the CAS number, chemical name, formula, and molecular weight on the supplier’s specification documents.
• Match the requested assay and impurity limits to the intended reaction and downstream use.
• Ask for a quotation that states pack size, minimum order quantity, lead time, shipping terms, and available documentation.
• For scale-up or regulated workflows, assess handling, storage, and documentation requirements before placing an order.

Who This Guide Is For

This guide is intended for procurement teams, research and development chemists, process chemists, and distributors evaluating 4-Trifluoromethoxyphenylboronic acid. It provides a practical framework for comparing product offers without assuming that every supplier provides the same grade, packaging, or documentation. The guidance is relevant whether you are purchasing for an initial laboratory evaluation or planning a larger campaign. Actual availability and commercial terms should be confirmed directly with the supplier.

What Is 4-Trifluoromethoxyphenylboronic Acid?

This compound is an aromatic boronic acid: a phenyl ring bearing a boronic acid group and a trifluoromethoxy substituent in the para position. In a suitable palladium-catalyzed Suzuki–Miyaura reaction, the aryl group can participate in carbon–carbon bond formation with an appropriate coupling partner. The outcome depends on the complete reaction system, including substrates, catalyst, base, solvent, and operating conditions. The compound is a building block, not a guarantee of a particular reaction yield or product performance.

Identity at a Glance

Applications and Product Matching

Buyers most commonly assess this material as a boronic acid coupling partner for synthetic chemistry. The para-trifluoromethoxy substituent is part of the molecule’s structure and may be relevant when designing compounds that require this specific substitution pattern. Whether the material is appropriate for a given route must be evaluated by the project chemist through literature review, reaction screening, or established process knowledge. Do not select it solely because a product name resembles another arylboronic acid.

Match the Grade to the Work

For early research, the key requirement may be sufficient identity confirmation and an assay suitable for exploratory reactions. For process development, buyers may need tighter impurity controls, lot consistency, defined analytical methods, and a larger or repeatable supply plan. If the material will enter a regulated or quality-controlled workflow, confirm required documentation and acceptance criteria before issuing a purchase order. Requirements should be agreed in writing rather than inferred from a product listing.

Buyer Selection Framework

1. Confirm Chemical Identity

Start by checking that the supplier’s quotation and specification identify CAS 139301-27-2 and the requested para-substituted compound. Review the molecular formula and molecular weight as cross-checks, while recognizing that these identifiers do not replace appropriate analytical documentation. If your internal system uses a preferred name or product code, provide it alongside the CAS number. This reduces the risk of confusion with related boronic acids or positional isomers.

2. Set Assay and Impurity Requirements

Request the assay method and the reported result for the offered lot, if available. Ask which impurities are measured or controlled and whether the supplier can evaluate project-specific limits. A single purity percentage does not describe every impurity, moisture level, or analytical method, so compare like with like. For demanding applications, have your technical team review the specification before procurement approval.

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3. Check Packaging, Storage, and Handling

Confirm the available pack sizes and whether packaging is appropriate for the amount and handling conditions required by your site. Consult the supplier’s safety data sheet and product documentation for handling, storage, and transport guidance; do not rely on generic assumptions about boronic acids. If you plan to retain material between campaigns, clarify recommended storage conditions and any stated retest or expiry information. Your EHS and quality teams should review these details before receipt and use.

4. Plan Quantity and Timing

Estimate the quantity required for reaction screening, development, repeat experiments, and contingency before requesting a quotation. Ask the supplier to state the minimum order quantity, quoted pack size, current lead time, and whether the quoted material is available from stock or subject to procurement. These terms can vary by order size, destination, and supply conditions. For time-sensitive projects, request confirmation of the expected dispatch window and shipping options in writing.

Pricing, MOQ, and Lead Time

There is no reliable universal price or lead time for this product because commercial terms can depend on quantity, grade, packaging, destination, and current availability. A lower unit price may not represent the best overall value if the offered specification, documentation, or delivery schedule does not meet project needs. Compare quotations using the same assay target, pack quantity, delivery destination, and documentation requirements. Ask suppliers to identify any assumptions or exclusions in their offer.

For a useful quotation request, provide your required quantity, target specification, intended application, destination, and preferred delivery date. If you need a sample or evaluation quantity, state that separately from any expected commercial demand. Maison Chemical can review these details and advise what product information and supply options can be discussed for your inquiry. Availability, minimum quantities, and delivery commitments should be confirmed at the time of quotation.

Supplier Evaluation Checklist

• Does the offer clearly state the product name and CAS 139301-27-2?
• Can the supplier provide a current specification and lot-specific analytical documentation, where available?
• Are assay, impurity, packaging, and storage requirements clearly described?
• Are MOQ, price basis, lead time, shipping terms, and quotation validity stated?
• Can the supplier discuss repeat-order planning or project-specific requirements?
• Are safety and transport documents available for review before shipment?

Common Purchasing Mistakes to Avoid

One frequent mistake is treating the CAS number as the only purchasing criterion. Identity is essential, but buyers also need a specification that fits the intended use and a clear understanding of the lot’s analytical evidence. Another risk is comparing purity values without checking the analytical method or whether impurity limits are relevant to the project. Finally, waiting until material is urgently needed to confirm MOQ, documentation, and shipping can create avoidable schedule pressure.

Conclusion: What to Do Next

4-Trifluoromethoxyphenylboronic acid CAS 139301-27-2 is an arylboronic acid building block considered for Suzuki–Miyaura and related synthetic planning, with an approximate molecular weight of 205.93 g/mol. To buy it confidently, confirm chemical identity, define assay and impurity expectations, review handling documentation, and compare quotations on an equivalent basis. The right supplier choice depends on the specifications and delivery conditions your project actually requires. Send Maison Chemical your target quantity, specification, destination, and timing to request product information and a B2B quotation.